A soft gel capsule formulated using 0.25 mg of Calcitrol and 500 mg of calcium citrate maleate and 50 mg of magnesium oxide and 7.5 mg of zinc oxide.
Calcium plays a critical role in the body. It is essential for normal functioning of nerves, cells, muscle and bone.
Calcium and vitamin D preparations are used to prevent or to treat calcium deficiency. A vitamin D resistant state may exist in uremic patients because of the failure of the kidney to adequately produce calcitriol.
Calcium citrate malate is a water-soluble calcium supplement. It is the calcium salt of citric acid & malic acid and is highly bioavailable. Calcium citrate malate when dissolved, it releases calcium ions and a calcium-citrate complex. Calcium ions are absorbed directly into intestinal cells, and the citrate complex enters the body through paracellular (passing through the intercellular space between the cells) absorption.
Calcium citrate malate is approximately (4-5%) more absorbable than calcium carbonate and is well absorbed regardless of stomach acid. Studies have suggested that calcium citrate malate is better absorbed than calcium carbonate and that the citrate form might thus be more effective in helping to prevent or ameliorate osteoporosis.
Calcitriol is the active from of vitamin D3 (cholecalciferol). It is produced in the kidney from the vitamin D metabolite 25-hydroxyvitamin D3 (calcifediol). Vitamin D is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.
The known sites of action of calcitriol are intestine, bone, kidney and parathyroid gland. In bone, calcitriol in conjunction with parathyroid hormone stimulates resorption of calcium; and in the kidney, calcitriol increases the tubular reabsorption of calcium.
Zinc is a nutritional supplement important for normal growth and tissue repair. Urinary elimination of zinc is increased in osteoporotic women. Zinc depletion is shown to diminish the response of oral calcitriol when administered orally. Supplementary zinc not only improves calcitriol response but also helps to arrest bone loss in old postmenopausal women.
Bones with Osteoporosis have low Magnesium content. Hence, it is essential to supplement Magnesium in Osteoporosis to maintain the integrity of bones.
Treatment by Condition Related to Calcium Citrate Malate-Vitamin D3
Prevention of Vitamin D Deficiency Medications
Post-Menopausal Osteoporosis Prevention Medications
Prevention of a Low Amount of Calcium in the Blood Medications
Vitamin D Deficiency Medications
Low Amount of Calcium in the Blood Medications